Long-term DM1 patients with no DR maintained visual function, with a decrease in VA with 1.25% ETDRS contrast. Differences were found in the IRL with no changes in the outer ones. Retinal thicknesses in the central area and in the vertical outer areas were higher in the DM1 group. Both ETDRS 2.5% and color vision were lower in the DM1 group but did not reach statistical significance. Visual acuity (VA) with ETDRS 1.25% was lower in the DM1 patients. The mean ages were 42.93 ± 13.62 and 41.52 ± 13.05 years in the diabetic and control groups, respectively. Functional tests were performed in both groups, including ETDRS with 100, 2.5 and 1.25% contrast, and color vision. Ninety DM1 and 60 healthy eyes were evaluated using spectral domain (SD)-OCT and swept source (SS)-OCT to measure changes in the retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL) and inner nuclear layer (INL) thicknesses in all Early Treatment of Diabetic Retinopathy Study (ETDRS) macular areas.

To evaluate changes in inner retinal layer (IRL) thicknesses in patients with type 1 diabetes mellitus (DM1) with no diabetic retinopathy (DR) using two different optical coherence tomography (OCT) devices.

Difference between dm1 and dm2